What is Sickle Cell Disease (SCD)?
Types of Sickle Cell Disease
People who have this form of SCD inherit two sickle cell genes (“S”), one from each parent. This is commonly called sickle cell anemia and is usually the most severe form of the disease.
People who have this form of SCD inherit a sickle cell gene (“S”) from one parent and from the other parent a gene for an abnormal hemoglobin called “C”. Hemoglobin is a protein that allows red blood cells to carry oxygen to all parts of the body. This is usually a milder form of SCD.
Hemoglobin S beta thalassemia
People who have this form of SCD inherit one sickle cell gene (“S”) from one parent and one gene for beta thalassemia, another type of anemia, from the other parent. There are two types of beta thalassemia: “0” and “+”. Those with HbS beta 0-thalassemia usually have a severe form of SCD. People with HbS beta +-thalassemia tend to have a milder form of SCD.
Hemoglobin SD, Hemoglobin SE, and Hemoglobin SO
People who have these forms of SCD inherit one sickle cell gene (“S”) and one gene from an abnormal type of hemoglobin (“D”, “E”, or “O”). Hemoglobin is a protein that allows red blood cells to carry oxygen to all parts of the body. The severity of these rarer types of SCD varies.
Sick Cells – The Documentary
Sick Cells began as a full-length documentary project before it morphed into a national advocacy organization. The team intended to spread awareness about the disease by showing the impacts of SCD on Marqus' life. However, the team decided to put Sick Cells Documentary on hold after learning more about other people's lives with SCD. The team realized that there are many types of stories, types of SCD, types of families, and types of ways that the sickle cell community has thrived. The team wanted to capture more stories and elevate more voices before creating a documentary.
Although this clip is just a taste of the full documentary that was storyboarded for, the team plans to create another full-length documentary that includes various people’s journey with SCD. #TeamSickCells hopes to highlight diversity within the disease and underscore the resilience of the community.
Thank you for watching our documentary. Sick Cells has come a very long way since the creation of this documentary. We are now a 501 (C) (3) Organization that strives to elevate the voices of the sickle cell disease (SCD) community and their stories of resilience. Through actions like this creating documentary, featuring the Faces of SCD of our website, and educating the public, we aim to ignite interest around the disease. In highlighting the grave disparities this community faces, we hope to improve the quality of life and care for people living with the most common genetic disorder by influencing decision-makers and propelling change.